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GPX4 inhibitor 24

Chemical Structure : GPX4 inhibitor 24

CAS No.:

GPX4 inhibitor 24

Catalog No.: PC-20267Not For Human Use, Lab Use Only.

GPX4 inhibitor 24 is a potent glutathione peroxidase 4 (GPX4) inhibitor, induces ferroptosis in vivo.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GPX4 inhibitor 24 is a potent glutathione peroxidase 4 (GPX4) inhibitor, induces ferroptosis in vivo.

Physicochemical Properties

M.Wt 460.93
Formula C22H21ClN2O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

methyl (1S,3R)-2-(2-chloroacetyl)-1-(4-(methylsulfonyl)phenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate

References

1. Randolph JT, et al. J Med Chem. 2023 Mar 6. doi: 10.1021/acs.jmedchem.2c01415.

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