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Chemical Structure : GSK-467
CAS No.: 1628332-52-4
Catalog No.: PC-62292Not For Human Use, Lab Use Only.
GSK-467 is a potent, selective KDM5 inhibitor with Ki of 10 nM, shows 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other JmJ family members.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $248 | In stock | |
| 25 mg | $398 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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GSK-467 (GSK467) is a potent, selective KDM5 inhibitor with Ki of 10 nM, shows 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other JmJ family members.
GSK-467 (GSK467) increases the rate of apoptosis in myeloma cells.
| M.Wt | 319.32 | |
| Formula | C17H13N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-[(1-Benzyl-1H-pyrazol-4-yl)oxy]-pyrido-[3,4-d]pyrimidin-4(3H)-one |
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1. Johansson C, et. Nat Chem Biol. 2016 Jul;12(7):539-45.
2. Westaway SM, et al. J Med Chem. 2016 Feb 25;59(4):1370-87.
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