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GSK-625433

Chemical Structure : GSK-625433

CAS No.: 885264-71-1

GSK-625433 (GSK 625433;GSK625433)

Catalog No.: PC-60425Not For Human Use, Lab Use Only.

A highly potent, selective HCV NS5B polymerase inhibitor for treatment of HCV infection..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A highly potent, selective HCV NS5B polymerase inhibitor for treatment of HCV infection.

HCV Infection

Phase 1 Discontinued

Physicochemical Properties

M.Wt 512.62
Formula C26H32N4O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2R,4R,5S)-1-(4-tert-butyl-3-methoxybenzoyl)-4-(methoxymethyl)-2-(pyrazol-1-ylmethyl)-5-(1,3-thiazol-2-yl)pyrrolidine-2-carboxylic acid

References

1. Parcella K, et al. ACS Med Chem Lett. 2017 Jun 29;8(7):771-774.

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