Chemical Structure : GSK2033
CAS No.:
1221277-90-2
GSK2033
(GSK-2033)
Catalog No. : PC-63084Not For Human Use, Lab Use Only.
GSK2033 (GSK 2033) is the first potent, cell-active LXR antagonist with binding pIC50 of 7.0/7.5 for LXRα/LXRβ, respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6308401
Biological Activity
GSK2033 (GSK 2033) is the first potent, cell-active LXR antagonist with binding pIC50 of 7.0/7.5 for LXRα/LXRβ, respectively.
Physicochemical Properties
M.Wt
591.66
Formula
C29H28F3NO5S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2,4,6-Trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]-N-[[5-(trifluoromethyl)-2-furanyl]methyl]benzenesulfonamide
References
1. Zuercher WJ, et al. J Med Chem
2. Griffett K, et al. Biochem Biophys Res Commun
3. Patel R, et al. Endocrinology
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