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Chemical Structure : GSK 2041706
Catalog No.: PC-60821Not For Human Use, Lab Use Only.
A potent, selective and orally bioavailable GPR119 agonist with EC50 of 4 nM, with good selectivity versus a battery of receptors, ion channels and enzymes.
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A potent, selective and orally bioavailable GPR119 agonist with EC50 of 4 nM, with good selectivity versus a battery of receptors, ion channels and enzymes; causes greater reductions in cumulative food intake and higher fed plasma GLP-1 and peptide tyrosine tyrosine levels and decreased plasma insulin and glucose-dependent insulinotropic polypeptide levels, when combined with metformin, in diet-induced obese mice.
| M.Wt | 471.576 | |
| Formula | C23H29N5O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Al-Barazanji K, et al. J Pharmacol Exp Ther. 2015 Jun;353(3):496-504.
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