GT-01956 | GSPT1 degrader | Probechem Biochemicals

Chemical Structure : GT-01956

GT-01956 (GT01956)

Catalog No.: PC-28743Not For Human Use, Lab Use Only.

GT-01956 is a potent, selective BET-targeting PROTAC degrader with picomolar degradation potency, shows exceptional anti-proliferative activity across hematologic and solid tumor cell lines.

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Biological Activity

GT-01956 is a potent, selective BET-targeting PROTAC degrader with picomolar degradation potency, shows exceptional anti-proliferative activity across hematologic and solid tumor cell lines.

Physicochemical Properties

M.Wt	744.33
Formula	C37H38ClN7O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-4-yl]thio]pentyl]-2,3,9-trimethyl-, (6S)-

References

1. Renhong Sun, et al. RSC Med Chem. 2026 Oct 19. doi: 10.1039/d6md00636a.

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GT-01956 (GT01956)

Biological Activity

Physicochemical Properties

References

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