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Galvestine-1

Chemical Structure : Galvestine-1

CAS No.: 1087311-82-7

Galvestine-1 (Galvestine1)

Catalog No.: PC-62193Not For Human Use, Lab Use Only.

Galvestine-1 is a small molecule MGDG (monogalactosyldiacylglycerol) synthase inhibitor with IC50 of 10 uM by competing with diacylglycerol binding.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Galvestine-1 is a small molecule MGDG (monogalactosyldiacylglycerol) synthase inhibitor with IC50 of 10 uM by competing with diacylglycerol binding; shows effect of root uptake, circulation in the xylem and mesophyll, inhibition of MGDs in vivo causing a reduction of MGDG content and impairment of chloroplast development in Arabidopsis thaliana; a unique tool to study lipid homeostasis in plants.

Physicochemical Properties

M.Wt 498.627
Formula C30H34N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

[(2S)-2-(dibenzylamino)propyl] 4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxylate

References

1. Botté CY, et al. Nat Chem Biol. 2011 Sep 25;7(11):834-42.

2. Boudière L, et al. Mol Biosyst. 2012 Aug;8(8):2023-35, 2014.

3. Botella C, et al. Plant Physiol. 2016 Mar;170(3):1300-14.

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