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Chemical Structure : GlyH-101
CAS No.: 328541-79-3
Catalog No.: PC-45455Not For Human Use, Lab Use Only.
A potent CFTR inhibitor with Ki of 4.3 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $100 | In stock | |
| 50 mg | $416 | In stock |
Bulk size, bulk discount!
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A potent CFTR inhibitor with Ki of 4.3 uM; rapidly and reversibly inhibited forskolin-induced hyperpolarization in nasal potential differences in mice; effectively reduces cholera toxin-induced intestinal fluid secretion in a closed-loop model of cholera.
| M.Wt | 493.1487 | |
| Formula | C19H15Br2N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 58 mg/mL |
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| Chemical Name/SMILES |
Glycine, N-2-naphthalenyl-, 2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide |
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1. Muanprasat C, et al. J Gen Physiol. 2004 Aug;124(2):125-37.
2. Norimatsu Y, et al. Mol Pharmacol. 2012 Dec;82(6):1042-55.
3. Barman PP, et al. Biochem Biophys Res Commun. 2011 Apr 29;408(1):12-7.
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