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Chemical Structure : GpTx-1
Catalog No.: PC-63263Not For Human Use, Lab Use Only.
GpTx-1 is a potent, selective, 34-residue peptide antagonist of Nav1.7 sodium channel with IC50 of 10 nM, displays 20- and 1000- fold selectivity over NaV1.4 and NaV1.5..
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GpTx-1 is a potent, selective, 34-residue peptide antagonist of Nav1.7 sodium channel with IC50 of 10 nM, displays 20- and 1000- fold selectivity over NaV1.4 and NaV1.5.
| M.Wt | ||
| Formula | C176H271N53O45S7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Murray JK, et al. J Med Chem. 2015 Mar 12;58(5):2299-314.
2. Deuis JR, et al. Toxins (Basel). 2016 Mar 17;8(3). pii: E78.
3. Biswas K, et al. ACS Chem Biol. 2017 Sep 15;12(9):2427-2435.
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