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Chemical Structure : Guanabenz
CAS No.: 5051-62-7
Catalog No.: PC-62319Not For Human Use, Lab Use Only.
Guanabenz (WY 8678) is an α2 adrenergic receptor agonist that is used as an antihypertensive agent, also has been proposed to exert protective effects against misfolding by interfering with eIF2α-P dephosphorylation through selective disruption of a PP1-PPP1R15A holophosphatase complex.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $98 | In stock | |
| 200 mg | $148 | In stock | |
| 500 mg | Get quote | ||
| 1 g | Get quote |
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Guanabenz (WY 8678) is an α2 adrenergic receptor agonist that is used as an antihypertensive agent, also has been proposed to exert protective effects against misfolding by interfering with eIF2α-P dephosphorylation through selective disruption of a PP1-PPP1R15A holophosphatase complex.
Guanabenz also has antiparasitic activity against replicative stages of Toxoplasma.
| M.Wt | 231.08 | |
| Formula | C8H8Cl2N4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine |
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1. Das I, et al. Science. 2015 Apr 10;348(6231):239-42.
2. Crespillo-Casado A, et al. Elife. 2017 Apr 27;6. pii: e26109.
3. Benmerzouga I, et al. Antimicrob Agents Chemother. 2015 Nov;59(11):6939-45.
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