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Chemical Structure : H-1152
CAS No.: 451462-58-1
Catalog No.: PC-44656Not For Human Use, Lab Use Only.
A potent and selective ROCK inhibitor with Ki of 1.6 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $201.6 | In stock |
Bulk size, bulk discount!
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A potent and selective ROCK inhibitor with Ki of 1.6 nM; shows poor inhibition on other serine/threonine kinases; inhibits the phosphorylation of MARCKS in human neuroteratoma (NT-2) cells stimulated by Rho-activator lysophosphatidic acid.
| M.Wt | 319.4218 | |
| Formula | C16H21N3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Isoquinoline, 5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-methyl- |
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1. Ikenoya M, et al. J Neurochem. 2002 Apr;81(1):9-16.
2. Wang HL, et al. Neuropharmacology. 2013 Jul;70:1-11.
3. Sheikh IA, et al. J Biol Chem. 2013 Jul 12;288(28):20404-15.
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