Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : HER2-IN-2
Catalog No.: PC-62303Not For Human Use, Lab Use Only.
HER2-IN-2 is a potent, selective HER2 inhibitor, only shows potent inhibition for EGFR and Abl in a panel of kinases.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
HER2-IN-2 is a potent, selective HER2 inhibitor, only shows potent inhibition for EGFR and Abl in a panel of kinases; equipotent to lapatinib against HER2 in vitro, also able to inhibit the small amount of HER3 auto-phosphorylation; inhibits 2YF/3TM gatekeeper mutant Ba/F3 cells lines with IC50 of 18.63 nM.
| M.Wt | 373.372 | |
| Formula | C20H15N5O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Novotny CJ, et al. Nat Chem Biol. 2016 Nov;12(11):923-930.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
