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Chemical Structure : HER2-IN-3
Catalog No.: PC-62304Not For Human Use, Lab Use Only.
HER2-IN-3 is a type I HER2 inhibitor that has a similar profile to HER2-IN-2.
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HER2-IN-3 is a type I HER2 inhibitor that has a similar profile to HER2-IN-2; shows superior activity to lapatinib in the 2YF/3wt + NRG cells and specificity for this cell line; remains sensitivity to HER2 mutations L755S (2YF-L755S/3wt), Y772_A775 dup (2YF-YVMA/3wt), and G776del_insVC (2YF-VC/3wt) cells.
| M.Wt | 372.388 | |
| Formula | C20H16N6O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Novotny CJ, et al. Nat Chem Biol. 2016 Nov;12(11):923-930.
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