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Chemical Structure : HJC 0197
Catalog No.: PC-63108Not For Human Use, Lab Use Only.
HJC 0197 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 4.0 uM.
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HJC 0197 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 4.0 uM; also inhibits EPAC1-mediated Rap1-GDP exchange activity; does not alter cAMP-induced type I and II PKA holoenzymes activation at 25 uM.
| M.Wt | 339.457 | |
| Formula | C19H21N3OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Chen H, et al. J Med Chem. 2014 May 8;57(9):3651-65.
2. Chen H, et al. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4038-43.
3. Juhász T, et al. Cell Signal. 2014 Mar;26(3):468-82.
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