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HN252

Chemical Structure : HN252

CAS No.:

HN252 (HN 252)

Catalog No.: PC-20365Not For Human Use, Lab Use Only.

HN252 is a potent protein phosphatase 1B (PPM1B) inhibitor with Ki of 0.52 uM and IC50 of 0.76 uM, shows no inhibition against topoisomerases in vitro.

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Biological Activity

HN252 is a potent protein phosphatase 1B (PPM1B) inhibitor with Ki of 0.52 uM and IC50 of 0.76 uM, shows no inhibition against topoisomerases in vitro.

Physicochemical Properties

M.Wt 321.33
Formula C19H15NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-amino-3'',4''-dihydroxy-[1,1':4',1''-terphenyl]-4-carboxylic acid

References

1. Zhiyuan Lu, et al. J Cell Mol Med. 2020 Nov;24(22):13463-13471.

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