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HTS13286

Chemical Structure : HTS13286

CAS No.: 727359-12-8

HTS13286 (HTS 13286)

Catalog No.: PC-20302Not For Human Use, Lab Use Only.

HTS13286 is a selective AQP9 inhibitor with IC50 of 1.5 uM (inhibition of CHO-AQP9 cell water permeability).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

HTS13286 is a selective AQP9 inhibitor with IC50 of 1.5 uM (inhibition of CHO-AQP9 cell water permeability).
HTS13286 shows little to no activity against AQP3, AQP7, and AQP8.

Physicochemical Properties

M.Wt 415.51
Formula C16H13N7OS3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(5-(thiophen-2-yl)-1,3,4-thiadiazol-2-yl)acetamide

References

1. Sabina Jelen, et al. J Biol Chem. 2011 Dec 30;286(52):44319-25.

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