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Chemical Structure : HhAg1.5
Catalog No.: PC-49040Not For Human Use, Lab Use Only.
HhAg1.5 (SAg1.5) is a small molecule Hedgehog agonist with EC50 of 1 nM, induces cilia translocation of SMO and GLI transcription factor activation, efficiently generates expandable liver stem cells (LSCs) in vitro.
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HhAg1.5 (SAg1.5) is a small molecule Hedgehog agonist with EC50 of 1 nM, induces cilia translocation of SMO and GLI transcription factor activation, efficiently generates expandable liver stem cells (LSCs) in vitro.
| M.Wt | 526.043 | |
| Formula | C28H26ClF2N3OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Wang C, et al. Nat Commun. 2014 Jul 10;5:4355.
2. Liu J, et al. Onco Targets Ther. 2020 Nov 19;13:11957-11973.
3. Abhisek Mitra, et al. Transl Res. 2019 Mar;205:44-50.
4. Frank-Kamenetsky M, et al. J Biol. 2002;1:10.
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