I-BET432

Chemical Structure : I-BET432

Catalog No.: PC-49467Not For Human Use, Lab Use Only.

I-BET432 is a potent, highly ligand-efficient, orally active pan-BET bromodomain inhibitor.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

I-BET432 is a potent, highly ligand-efficient, orally active pan-BET bromodomain inhibitor.

M.Wt	327.384
Formula	C18H21N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-7-((R)-1,2-dihydroxyethyl)-1,3-dimethyl-5-(1-methyl-1H-pyrazol-4-yl)-1,3-dihydro-2H-benzo[d]azepin-2-one

1. Philip G. Humphreys, et al. J. Med. Chem. 2022.