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ICA73

Chemical Structure : ICA73

CAS No.: 1028312-34-6

ICA73 (ICA-069673, ICA069673)

Catalog No.: PC-26105Not For Human Use, Lab Use Only.

ICA‐069673 (ICA73) is a selective activator of KCNQ2 potassium channel (Kv7.2), acts within the voltage-sensor domain (VSD), shows selective effects on KCNQ2 over KCNQ3.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ICA‐069673 (ICA73) is a selective activator of KCNQ2 potassium channel (Kv7.2), acts within the voltage-sensor domain (VSD), shows selective effects on KCNQ2 over KCNQ3.

Physicochemical Properties

M.Wt 251.65
Formula C11H7ClFN3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-chloropyrimidin-5-yl)-4-fluorobenzamide

References

1. Wang AW, et al. J Physiol. 2017 Feb 1;595(3):663-676.

2. Wang CK, et al. J Gen Physiol. 2018 Dec 3;150(12):1722-1734.

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