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IDD388

Chemical Structure : IDD388

CAS No.: 314297-26-2

IDD388 (IDD 388)

Catalog No.: PC-62882Not For Human Use, Lab Use Only.

IDD388 is a potent aldose reductase (ALR2 or AKR1B1) inhibitor with IC50 of 0.4 uM, shows weak inhibition for AKR1B10 (IC50=4.4 uM)..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

IDD388 is a potent aldose reductase (ALR2 or AKR1B1) inhibitor with IC50 of 0.4 uM, shows weak inhibition for AKR1B10 (IC50=4.4 uM).

Physicochemical Properties

M.Wt 416.627
Formula C16H12BrClFNO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(2-((4-bromo-2-fluorobenzyl)carbamoyl)-5-chlorophenoxy)acetic acid

References

1. Steuber H, et al. J Mol Biol. 2008 Jun 20;379(5):991-1016.

2. Cousido-Siah A, et al. ACS Chem Biol. 2016 Oct 21;11(10):2693-2705.

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