IHCH-1906 | 5-HT2A agonist | Probechem Biochemicals

Chemical Structure : IHCH-1906

IHCH-1906 (IHCH1906)

Catalog No.: PC-28310Not For Human Use, Lab Use Only.

IHCH-1906 is a potent agonist of serotonin 2A receptor (5-HT2AR) with Gq EC50 of 12.6 nM (Emax = 85%) and β-arrestin2 recruitment EC50 of 75.9 nM (Emax = 78%), shows antagonist activity at 5-HT2BR, partial agonist at 5-HT1DR (EC50 = 72.4 nM, Emax = 56%), and minimal activity at other receptors.

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Biological Activity

Physicochemical Properties

M.Wt	243.35
Formula	C16H21NO
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(1,2,3,6-tetrahydropyridin-4-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-1-ol

References

1. Tang L, et al. Nat Commun. 2026 Sep 17;17(1):9873.

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IHCH-1906 (IHCH1906)

Biological Activity

Physicochemical Properties

References

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