Chemical Structure : IHCH-7113
CAS No.: 313368-85-3
Catalog No.: PC-28307Not For Human Use, Lab Use Only.
IHCH-7113 is a selective agonist of serotonin 2A receptor (5-HT2AR) with EC50 of 58.9 nM in Gq BRET assay and 44.7 nM in β-arrestin 2 BRET assays, activates both Gαq-mediated signaling pathways and β-arrestin 2 recruitment pathways and shows antidepressant activity.
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IHCH-7113 is a selective agonist of serotonin 2A receptor (5-HT2AR) with EC50 of 58.9 nM in Gq BRET assay and 44.7 nM in β-arrestin 2 BRET assays, activates both Gαq-mediated signaling pathways and β-arrestin 2 recruitment pathways and shows antidepressant activity.
| M.Wt | 229.33 | |
| Formula | C14H19N3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(6bR,10aS)-3-Methyl-2,3,6b,7,8,9,10,10a-octahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline |
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1. Dongmei Cao, et al. Science. 2022 Jan 28;375(6579):403-411.
2. Duan W, et al. Chemical reviews. 2024 Jan 10;124(1):124-163.

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