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Chemical Structure : IKK2-IN-8
Catalog No.: PC-63117Not For Human Use, Lab Use Only.
IKK2-IN-8 is a potent, selective IKK2 inhibitor with IC50 of 6 nM, displays >40-fold selectivity over IKK1 (IC50=230 nM).
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IKK2-IN-8 is a potent, selective IKK2 inhibitor with IC50 of 6 nM, displays >40-fold selectivity over IKK1 (IC50=230 nM); inhibits lipopolysaccharide (LPS) induced TNFα production in human PBMCs with IC50 of 80 nM.
| M.Wt | 380.47 | |
| Formula | C19H20N6OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Dyckman AJ, et al. Bioorg Med Chem Lett. 2011 Jan 1;21(1):383-6.
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