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Chemical Structure : Ibiglustat
CAS No.: 1401090-53-6
Catalog No.: PC-61428Not For Human Use, Lab Use Only.
Ibiglustat (Venglustat, Genz-682452) is an orally active, selective and potent Glucosylceramide synthase (GCS) inhibitor with central nervous system (CNS) access.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $198 | In stock | |
| 25 mg | $348 | In stock | |
| 50 mg | $548 | In stock | |
| 100 mg | Get quote |
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Ibiglustat (Venglustat, Genz-682452) is an orally active, selective and potent Glucosylceramide synthase (GCS) inhibitor with central nervous system (CNS) access.
Ibiglustat (Venglustat) exhibits significantly lower tissue levels of GL-3 and lyso-GL-3 and a delayed progression of a thermal nociceptive response in administered Fabry mice.
Ibiglustat (Venglustat) shows favorable pharmacological properties and safety profile.
| M.Wt | 389.49 | |
| Formula | C20H24FN3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(3S)-1-azabicyclo[2.2.2]octan-3-yl N-{2-[2-(4-fluorophenyl)- 1,3-thiazol-4-yl]propan-2-yl}carbamate |
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1. Ashe KM, et al. Mol Med. 2015 Apr 30;21:389-99.
2. Marshall J, et al. Mol Ther. 2016 Jun;24(6):1019-1029.
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