Chemical Structure : Icosabutate
CAS No.: 1253909-57-7
Catalog No.: PC-27329Not For Human Use, Lab Use Only.
Icosabutate is a dual FFAR1/FFAR4 (GPR40/GPR120) agonist with EC50 of 10 μM and 15.5 μM, respectively, also is a partial agonist of PPARα with EC50 of 208 nM, inhibits the arachidonic acid cascade and exhibits antioxidant and anti-apoptotic activities.
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|---|---|---|---|
| 5 mg | $188 | In stock | |
| 10 mg | $298 | In stock | |
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Icosabutate is a dual FFAR1/FFAR4 (GPR40/GPR120) agonist with EC50 of 10 μM and 15.5 μM, respectively, also is a partial agonist of PPARα with EC50 of 208 nM, inhibits the arachidonic acid cascade and exhibits antioxidant and anti-apoptotic activities.
| M.Wt | 374.57 | |
| Formula | C24H38O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-(((5Z,8Z,11Z,14Z,17Z)-Icosa-5,8,11,14,17-pentaen-1-yl)oxy)butanoic acid |
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1. Harrison SA, et al. J Hepatol. 2025 Aug;83(2):293-303.
2. Stokman G, et al. Liver Int. 2020 Nov;40(11):2860-2876.
3. van den Hoek AM, et al. Hepatol Commun. 2019 Dec 24;4(2):193-207.

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