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Imrecoxib

Chemical Structure : Imrecoxib

CAS No.: 395683-14-4

Imrecoxib (BAP-909, BAP909)

Catalog No.: PC-28047Not For Human Use, Lab Use Only.

Imrecoxib (BAP-909) is a non-steroidal anti-inflammatory drug (NSAID) and moderately selective cyclooxygenase 2 (COX-2) inhibitor with IC50 of 115 nM and 18 nM for COX-1 and COX-2 respectively, selectively and dose-dependently inhibits COX-2 mRNA level, possesses anti-inflammatory effect.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Imrecoxib (BAP-909) is a non-steroidal anti-inflammatory drug (NSAID) and moderately selective cyclooxygenase 2 (COX-2) inhibitor with IC50 of 115 nM and 18 nM for COX-1 and COX-2 respectively, selectively and dose-dependently inhibits COX-2 mRNA level, possesses anti-inflammatory effect.

Physicochemical Properties

M.Wt 369.48
Formula C21H23NO3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(4-(Methylsulfonyl)phenyl)-1-propyl-3-(p-tolyl)-1,5-dihydro-2H-pyrrol-2-one

References

1. Chen XH, et al. Acta Pharmacol Sin. 2004 Jul;25(7):927-31.

2. Liu Y, et al. Sci Rep. 2019 Oct 31;9(1):15774.

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