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Chemical Structure : Indoluidin D
Catalog No.: PC-20263Not For Human Use, Lab Use Only.
Indoluidin D is a potent selective dihydroorotate dehydrogenase (DHODH) inhibitor, promotes myeloid differentiation and inhibits the proliferation of acute promyelocytic leukemia HL-60 cells.
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Indoluidin D is a potent selective dihydroorotate dehydrogenase (DHODH) inhibitor, promotes myeloid differentiation and inhibits the proliferation of acute promyelocytic leukemia HL-60 cells.
Indoluidin D also suppresses cell growth in various other types of cancer cells.
Indoluidin D inhibits human DHODH activity in vitro.
The DHODH reaction product orotic acid can rescue indoluidin D-induced cell differentiation.
| M.Wt | 452.56 | |
| Formula | C28H28N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Makoto Kawatani, et al. ACS Chem Biol. 2021 Nov 19;16(11):2570-2580.
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