Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Isobutyl-deoxynyboquinone
Catalog No.: PC-62342Not For Human Use, Lab Use Only.
Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1), produces ROS, and induces cytotoxicity in cancer cells in an NQO1-dependent manner.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1), produces ROS, and induces cytotoxicity in cancer cells in an NQO1-dependent manner.
IB-DNQ has improved solubility and biocompatibility in comparison with DNQ.
IB-DNQ is a superior drug candidate for evaluating anticancer activities and tolerability in vivo.
| M.Wt | 326.352 | |
| Formula | C18H18N2O4 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Parkinson EI, et al. Acc Chem Res. 2015 Oct 20;48(10):2715-23.
2. Lundberg AP, et al. Invest New Drugs. 2017 Apr;35(2):134-144.
3. Parkinson EI, et al. ACS Chem Biol. 2013 Oct 18;8(10):2173-83.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
