Chemical Structure : JNK-IN-8
CAS No.: 1410880-22-6
Catalog No.: PC-43490Not For Human Use, Lab Use Only.
JNK-IN-8 (JNK Inhibitor XVI) is a potent, selective, pan-JNK inhibitor with IC50 of 4.7 nM, 18.7 nM and 1 nM for JNK1, JNK2 and JNK3, respectively.
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| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | $558 | In stock | |
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JNK-IN-8 (JNK Inhibitor XVI) is a potent, selective, pan-JNK inhibitor with IC50 of 4.7 nM, 18.7 nM and 1 nM for JNK1, JNK2 and JNK3, respectively.
JNK Inhibitor XVI exhibits exceptional selectivity based upon KinomeScan and enzymatic profiling.
JNK Inhibitor XVI inhibits c-Jun phosphorylation in HeLa and A375 cells with EC50 of 486 nM and 338 nM, respectively.
| M.Wt | 507.59 | |
| Formula | C29H29N7O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 35 mg/mL |
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| Chemical Name/SMILES |
Benzamide, 3-[[4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-N-[3-methyl-4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]- |
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1. Zhang T, et al. Chem Biol. 2012 Jan 27;19(1):140-54.

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