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JSD26

Chemical Structure : JSD26

CAS No.: 2353515-08-7

JSD26 (JSD-26)

Catalog No.: PC-21076Not For Human Use, Lab Use Only.

JSD26 is a selective S-nitroso-coenzyme A reductase 2 (SCoR2; AKR1A1) inhibitor with Ki of 93 nM, 10-fold selectivity over AKR1B1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

JSD26 is a selective S-nitroso-coenzyme A reductase 2 (SCoR2; AKR1A1) inhibitor with Ki of 93 nM, 10-fold selectivity over AKR1B1.

Physicochemical Properties

M.Wt 290.32
Formula C18H14N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C1NC2(C(N1)=O)C3=C(C4=C2C=CC=C4)C=CC(C5CC5)=C3

References

1. Hua-Lin Zhou, et al. J Med Chem. 2023 Apr 27;66(8):5657-5668.

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