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You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-JUN-1111
JUN-1111

Chemical Structure : JUN-1111

CAS No.: 874351-38-9

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JUN-1111

Catalog No.: PC-24875Not For Human Use, Lab Use Only.

JUN-1111 is an irreversible and selective Cdc25 phosphatase inhibitor with IC50 values of 0.38, 1.8, 0.66, 28, 37 µM for Cdc25A, Cdc25B, Cdc25C, VHR, PTP1B, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

JUN-1111 is an irreversible and selective Cdc25 phosphatase inhibitor with IC50 values of 0.38, 1.8, 0.66, 28, 37 µM for Cdc25A, Cdc25B, Cdc25C, VHR, PTP1B, respectively.

Physicochemical Properties

M.Wt 287.32
Formula C15H17N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

7-[[2-(4-Morpholinyl)ethyl]amino]-5,8-quinolinedione

References

1. Brisson M, et al. Mol Pharmacol. 2005 Dec;68(6):1810-20.

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