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JZ-1201

Chemical Structure : JZ-1201

CAS No.:

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JZ-1201 (JZ1201)

Catalog No.: PC-26559Not For Human Use, Lab Use Only.

JZ-1201 is a selective serotonin (5-HT)/norepinephrine (NE) reuptake inhibitor and partial agonist of the 5-HT1A receptor, selectively binds to the SERT, NET, and 5-HT1A receptor with Ki values of 1.62 nM, 0.87 nM, and 0.22 nM, exerts antidepressant-like effects.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    JZ-1201 is a selective serotonin (5-HT)/norepinephrine (NE) reuptake inhibitor and partial agonist of the 5-HT1A receptor, selectively binds to the SERT, NET, and 5-HT1A receptor with Ki values of 1.62 nM, 0.87 nM, and 0.22 nM, exerts antidepressant-like effects.

    Physicochemical Properties

    M.Wt 454.97
    Formula C26H28ClFN2O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (R)-7-((1-(2-chloro-4-fluorophenyl)piperidin-4-yl)(cyclopentyl)methoxy)quinolin-2(1H)-one

    References

    1. Gao H, et al. Naunyn Schmiedebergs Arch Pharmacol. 2026 Apr 15. doi: 10.1007/s00210-026-05333-6.

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