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Chemical Structure : K67
Catalog No.: PC-62796Not For Human Use, Lab Use Only.
K67 is a specific inhibitor of the interaction between S349-phosphorylated p62 and Keap1, exhibts no inhibitory effect on the interaction of full-length Keap1 with Nrf2-ETGE or full-length Nrf2.
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K67 is a specific inhibitor of the interaction between S349-phosphorylated p62 and Keap1, exhibts no inhibitory effect on the interaction of full-length Keap1 with Nrf2-ETGE or full-length Nrf2.
K67 has specific inhibitory effect on the Nrf2 target genes.
K67 dramatically suppresses the proliferations of Huh1 cells and of Huh7 cells expressing phospho-mimetic p62.
| M.Wt | 582.686 | |
| Formula | C29H30N2O7S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Saito T, et al. Nat Commun. 2016 Jun 27;7:12030.
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