KG022

Chemical Structure : KG022

Catalog No.: PC-25283Not For Human Use, Lab Use Only.

KG022 is a fluoroquinolone derivative, binds specifically to the bulge-out region of hairpin RNAs, binds to RNA-C and RNA-G stronger than RNA-A and RNA-U based on the exchange rates.

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Biological Activity

KG022 is a fluoroquinolone derivative, binds specifically to the bulge-out region of hairpin RNAs, binds to RNA-C and RNA-G stronger than RNA-A and RNA-U based on the exchange rates.

Physicochemical Properties

M.Wt	443.57
Formula	C24H34FN5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-cyclopropyl-N-(3-(dimethylamino)propyl)-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxamide

References

1. Ichijo R, et al. Biochemistry. 2025 May 20;64(10):2192-2199.

2. Nagano K, et al. J Biochem. 2022 Feb 21;171(2):239-244.

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KG022

Biological Activity

Physicochemical Properties

References

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