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Chemical Structure : KH 176
Catalog No.: PC-62601Not For Human Use, Lab Use Only.
KH176 (Sonlicromanol) is a chemical entity derivative of Trolox and small molecule ROS-redox modulator, shows potential treatment for mitochondrial disorders.
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KH176 (Sonlicromanol) is a chemical entity derivative of Trolox and small molecule ROS-redox modulator, shows potential treatment for mitochondrial disorders.
KH176 retains brain microstructural coherence in the external capsule in Ndufs4 -/- mice and normalizes the increased lipid peroxidation in this area and the cerebral cortex.
KH176 significantly improves rotarod and gait performance and reduces the degeneration of retinal ganglion cells in Ndufs4 -/- mice.
| M.Wt | 368.902 | |
| Formula | C19H29ClN2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. de Haas R, et al. Sci Rep. 2017 Sep 15;7(1):11733.
2. Koene S, et al. Orphanet J Rare Dis. 2017 Oct 16;12(1):163.
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