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Chemical Structure : KI-MS2-008
Catalog No.: PC-20800Not For Human Use, Lab Use Only.
KI-MS2-008 is a small molecule Max binder that modulate Myc-driven transcription in cells (IC50=1.28 uM) and inhibit viable cell levels in a Myc-dependent manner.
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KI-MS2-008 is a small molecule Max binder that modulate Myc-driven transcription in cells (IC50=1.28 uM) and inhibit viable cell levels in a Myc-dependent manner.
KI-MS2-008 induces Max/Max homodimerization.
KI-MS2-008 (10 uM) decreases Myc protein levels and affects the global Myc transcriptional program in ST486 cells.
KI-MS2-008 also decreases viable cancer cell growth in a Myc-dependent manner and suppresses tumor growth in vivo.
| M.Wt | 536.65 | |
| Formula | C32H28N2O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Struntz NB, et al. Cell Chem Biol. 2019 May 16;26(5):711-723.e14.
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