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KIN-1148

Chemical Structure : KIN-1148

CAS No.: 1428729-56-9

KIN-1148 (KIN 1148)

Catalog No.: PC-70231Not For Human Use, Lab Use Only.

KIN-1148 (KIN1148) is a small-molecule IRF3 agonist that induces dose-dependent IRF3 nuclear translocation and specific activation of IRF3-responsive promoters.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

KIN-1148 (KIN1148) is a small-molecule IRF3 agonist that induces dose-dependent IRF3 nuclear translocation and specific activation of IRF3-responsive promoters.
KIN-1148 functions as an influenza vaccine adjuvant by modulating the antiviral immune response.

Physicochemical Properties

M.Wt 361.437
Formula C19H11N3OS2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(benzo[1,2-d:3,4-d']bis(thiazole)-2-yl)-2-naphthamide

References

1. Probst P, et al. Vaccine. 2017 Apr 4;35(15):1964-1971.

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