KIT inhibitor 7

Chemical Structure : KIT inhibitor 7

Catalog No.: PC-27377Not For Human Use, Lab Use Only.

KIT inhibitor 7 is a potent, highly selective, orally bioavailable KIT inhibitor with IC50 of 2.8 nM, exhibits excellent broad kinome selectivity.

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Biological Activity

KIT inhibitor 7 is a potent, highly selective, orally bioavailable KIT inhibitor with IC50 of 2.8 nM, exhibits excellent broad kinome selectivity.

Physicochemical Properties

M.Wt	394.39
Formula	C20H16F2N6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-4-fluoro-2-methylphenyl)-6-fluoropyrazolo[1,5-a]pyridine-3-carboxamide

References

1. Chen KY, et al. J Med Chem. 2026 Jul 26. doi: 10.1021/acs.jmedchem.6c00898.

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KIT inhibitor 7

Biological Activity

Physicochemical Properties

References

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