KMCA-0011 | α2C adrenoceptor | Probechem Biochemicals

Chemical Structure : KMCA-0011

KMCA-0011 (KMCA0011)

Catalog No.: PC-28027Not For Human Use, Lab Use Only.

KMCA-0011 is a high potent α2C Adrenoceptor (α2C AR) antagonist with Ki of 56.7 nM, shows antidepressant activity and alleviates depressive behaviors by enhancing BDNF and synaptic plasticity.

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Biological Activity

KMCA-0011 is a high potent α2C Adrenoceptor (α2C AR) antagonist with Ki of 56.7 nM, shows antidepressant activity and alleviates depressive behaviors by enhancing BDNF and synaptic plasticity.

Physicochemical Properties

M.Wt	397.90
Formula	C22H24ClN3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-(4-benzylpiperidin-1-yl)ethyl)-5-chlorobenzo[d]oxazole-2-carboxamide

References

1. Kobeom Seo, et al. Bioorg Med Chem Lett. 2026 Feb 1:131:130467.

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KMCA-0011 (KMCA0011)

Biological Activity

Physicochemical Properties

References

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