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Chemical Structure : L-Propargylglycine
CAS No.: 198774-27-5
Catalog No.: PC-72155Not For Human Use, Lab Use Only.
L-Propargylglycine (L-PAG) is the most commonly used, covalently irreversible inhibitor inhibitor of cystathionine γ-lyase (CSE).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $128 | In stock | |
| 100 mg | $328 | In stock | |
| 250 mg | $498 | In stock | |
| 1 g | Get quote |
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L-Propargylglycine (L-PAG) is the most commonly used, covalently irreversible inhibitor inhibitor of cystathionine γ-lyase (CSE).
L-Propargylglycine (L-PAG) is also reported to suppress the activity of other B6 enzymes, i.e. aspartate aminotransferase and alanine aminotransferase.
L-Propargylglycine (L-PAG) dose-dependently inhibits endogenous CSE activity and decreases the H2S content in Raw264.7 macrophages with IC50 of 370 uM.
| M.Wt | 113.116 | |
| Formula | C5H7NO2 | |
| Appearance | Solid | |
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1. Antonia Asimakopoulou, et al. Br J Pharmacol. 2013 Jun;169(4):922-32.
2. Collin M, et al. Br J Pharmacol. 2005 Oct;146(4):498-505.
3. Bhatia M, et al. Br J Pharmacol. 2005 May;145(2):141-4.
4. Tamizhselvi R, et al. J Cell Mol Med. 2007 Mar-Apr;11(2):315-26.
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