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L-g-glutamyl-p-nitroanilide hydrochloride

Chemical Structure : L-g-glutamyl-p-nitroanilide hydrochloride

CAS No.: 67953-08-6

L-g-glutamyl-p-nitroanilide hydrochloride (GPNA)

Catalog No.: PC-61185Not For Human Use, Lab Use Only.

L-g-glutamyl-p-nitroanilide hydrochloride is a potent, competitive inhibitor of the neutral amino acid transporter ASCT2 (SLC1A5) with pKa of 13.79.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

L-g-glutamyl-p-nitroanilide hydrochloride is a potent, competitive inhibitor of the neutral amino acid transporter ASCT2 (SLC1A5) with pKa of 13.79.

Physicochemical Properties

M.Wt 303.699
Formula C11H14ClN3O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

L-Glutamine, N-(4-nitrophenyl)-, monohydrochloride (9CI)

References

1. Esslinger CS, et al. Bioorg Med Chem. 2005 Feb 15;13(4):1111-8.

2. Gao M, et al. Mol Cell. 2015 Jul 16;59(2):298-308.

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