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Chemical Structure : L524-0366
CAS No.: 951612-19-4
Catalog No.: PC-20808Not For Human Use, Lab Use Only.
L524-0366 is a small-molecule inhibitor of Fn14, binds specifically to the Fn14 receptor and disrupts TWEAK-Fn14 interaction.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $428 | In stock | |
| 25 mg | $658 | In stock | |
| 100 mg | Get quote |
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L524-0366 is a small-molecule inhibitor of Fn14, binds specifically to the Fn14 receptor and disrupts TWEAK-Fn14 interaction.
L524-0366 suppresses TWEAK-induced cell migration and survival in glioblastoma cells.
L524-0366 is a small molecule inhibitor to the TWEAK-Fn14 signaling axis.
| M.Wt | 308.78 | |
| Formula | C13H13ClN4OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
O=C(C1=CN(C2=CC=CC(Cl)=C2)N=N1)N3CCSCC3 |
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1. Ryne Holmberg, et al. Mol Cancer Res. 2023 Feb 1;21(2):170-186.
2. Harshil D. Dhruv, et al. Cancer Res (2014) 74 (19_Supplement): 1780.
3. Short C, et al. Hepatology. 2023 May 1;77(5):1639-1653.
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