LINS01022 | H3R antagonist | Probechem Biochemicals

Chemical Structure : LINS01022

LINS01022 (LINS-01022)

Catalog No.: PC-27866Not For Human Use, Lab Use Only.

LINS01022 is a high affinity, selective histamine H3 receptor (H3R) antagonist with pKi of 8.2, >1000-fold selective over H4R, exhibits potent antiproliferative effect against 4T1 and MDA-MB-231 TNBC cell lines.

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Biological Activity

Physicochemical Properties

M.Wt	288.39
Formula	C17H24N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-allyl-4-((5-methoxy-2,3-dihydrobenzofuran-2-yl)methyl)piperazine

References

1. Lopes FB, et al. Chem Biol Drug Des. 2022 Nov;100(5):722-729.

2. Ospital IA, et al. Biomed Pharmacother. 2024 May;174:116527.

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LINS01022 (LINS-01022)

Biological Activity

Physicochemical Properties

References

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