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LLY-2707

Chemical Structure LLY-2707

CAS No.: 1621865-33-5

LLY-2707 (LLY 2707;LLY2707)

Catalog No.: PC-60801Not For Human Use, Lab Use Only.

LLY-2707 (LLY 2707, LLY2707) is a novel potent, selective, nonsteroidal glucocorticoid receptor antagonist with Ki of 2.13 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

LLY-2707 (LLY 2707, LLY2707) is a novel potent, selective, nonsteroidal glucocorticoid receptor antagonist with Ki of 2.13 nM; shows substantially lower potency at the other steroid receptors (AR, MR and PR); suppress amphetamine-induced increases in locomotor activity, reduces atypical antipsychotic-associated weight gain in rats.

Physicochemical Properties

M.Wt 389.489
Formula C20H24FN3O2S
CAS No. 1621865-33-5
Storage
Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 3 Month
Shipping
Solubility

Chemical Name

N-(5-(tert-butyl)-3-(2-fluoro-5-methylpyridin-4-yl)-2-methyl-1H-indol-7-yl)methanesulfonamide

Clinical Information

References

1. Sindelar DK, et al. J Pharmacol Exp Ther. 2014 Jan;348(1):192-201.

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