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Chemical Structure : LOXO-195 RS-isomer
Catalog No.: PC-60902Not For Human Use, Lab Use Only.
The RS-isomer of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively..
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The RS-isomer of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.
| M.Wt | 380.427 | |
| Formula | C20H21FN6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Drilon A, et al. Cancer Discov. 2017 Sep;7(9):963-972.
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