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Chemical Structure : LOXO-195 R racemate
CAS No.: 1350884-56-8
Catalog No.: PC-60903Not For Human Use, Lab Use Only.
The R racemate of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $168 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | $528 | In stock | |
| 100 mg | $858 | In stock | |
| 1 g | Get quote |
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The R racemate of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.
| M.Wt | 380.427 | |
| Formula | C20H21FN6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
100 mM in DMSO (38 mg/mL) |
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| Chemical Name/SMILES |
(13E,14E,22S)-35-fluoro-6-methyl-7-aza-1(5,3)-pyrazolo[1,5-a]pyrimidina-3(3,2)-pyridina-2(1,2)-pyrrolidinacyclooctaphan-8-one |
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1. Drilon A, et al. Cancer Discov. 2017 Sep;7(9):963-972.
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