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Chemical Structure : LQB-118
Catalog No.: PC-60560Not For Human Use, Lab Use Only.
An orally active pterocarpanquinone that exhibits antitumoral and antileishmanial activity both in vitro and in vivo.
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An orally active pterocarpanquinone that exhibits antitumoral and antileishmanial activity both in vitro and in vivo; induces apoptosis in cells derived from chronic myeloid leukemia patients, exhibiting multifactorial drug resistance phenotype such as P-glycoprotein, MRP1 and p53 overexpression; shows activity active against intracellular amastigotes of L. amazonensis with IC50 of 1.4 uM, inhibits parasite growth in L.amazonensis-infected BALB/c mice.
| M.Wt | 304.3 | |
| Formula | C19H12O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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2. de Souza Reis FR, et al. Anticancer Agents Med Chem. 2013 Feb;13(2):341-51.
3. Martino T, et al. Bioorg Med Chem. 2014 Jun 15;22(12):3115-22.
4. Martino T, et al. Prostate. 2018 Feb;78(2):140-151.
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