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Chemical Structure : LXRβ agonist 17
Catalog No.: PC-61598Not For Human Use, Lab Use Only.
LXRβ agonist 17 is a potent, orally active liver X receptor β (LXRβ) agonist with Ki/EC50 of 3/21 nM, displays 27-fold selectivity over LXRα.
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LXRβ agonist 17 is a potent, orally active liver X receptor β (LXRβ) agonist with Ki/EC50 of 3/21 nM, displays 27-fold selectivity over LXRα.
LXRβ agonist 17 also exhibits excellent selectivity against other nuclear hormone receptors (>3,000-fold).
LXRβ agonist 17 induces the expression of LXR target genes in vitro and in vivo.
| M.Wt | 488.526 | |
| Formula | C21H27F3N4O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Zheng Y, et al. J Med Chem. 2016 Apr 14;59(7):3264-71.
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