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Chemical Structure : LY2922083
Catalog No.: PC-60238Not For Human Use, Lab Use Only.
LY2922083 is a potent, selective, orally available GPR40 agonist with EC50 of 9 nM.
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LY2922083 is a potent, selective, orally available GPR40 agonist with EC50 of 9 nM.
LY2922083 displays no activity against PPARα/β/γ (>10 uM).
LY2922083 demonstrates potent, efficacious, and durable dose-dependent reductions in glucose levels along with significant increases in insulin and GLP-1 secretion in vivo.
| M.Wt | 499.669 | |
| Formula | C31H33NO3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hamdouchi C, et al. J Med Chem. 2016 Dec 22;59(24):10891-10916.
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