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Chemical Structure : LY305
Catalog No.: PC-35133Not For Human Use, Lab Use Only.
LY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM, demonstrates potent agonist activity in the aforementioned C2C12 cellular assay (EC50=0.499 nM).
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LY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM, demonstrates potent agonist activity in the aforementioned C2C12 cellular assay (EC50=0.499 nM).
LY305 displays little to no affinity for GR, PR and MR (Ki>800 nM).
LY305 shows the desired muscle and prostate effects in a preclinical ORX rat model.
| M.Wt | 264.753 | |
| Formula | C14H17ClN2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Krishnan V, et al. Andrology. 2018 Mar 12. doi: 10.1111/andr.12479.
2. Saeed A, et al. J Med Chem. 2016 Jan 28;59(2):750-5.
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